Explore CAE04 Probionite

CAE04 Probionite

Gut & Sleep health.
in one sachet

Malaysia’s first 3-in-1 synbiotic system built to improve gut health and deeper rest.

Loved by 7000+ Customers

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Your sleep reflects the condition of your gut.

CAE04 Probionite targets your
body and gut for better sleep.

* 90% of serotonin is produced in the gut. It converts into melatonin at night—signaling the body to sleep.

Difference you can feel

Our Formulae: 3-in-1 Synbiotic Formulae

Probiotic

30B probiotic designed to build a stable gut.

Prebiotic

Non-fiber prebiotic feeds beneficial gut microbes.

Enzyme

Digestive enzymes break down food for a smoother gut.

10 Strains¹ For Transformative
Gut Benefits *

Probionite™ is formulated to rebuild the gut ecosystem linked to sleep, support deeper rest over time.*

Lactobacillus plantarum HP59

Gut barrier & nutrient absorption

Bifidobacterium lactis U9

Bloating & digestive regularity

Bifidobacterium lactis A6

Digestive comfort & microbiome balance

Lactobacillus casei CD22

Digestive efficiency & nutrient utilization

Lactobacillus rhamnosus T8

Support stress & mood balance

Bifidobacterium longum BB68S

Gut-brain and sleep support

Lactobacillus plantarum CR12

Inflammation & gut protection

Lactobacillus rhamnosus GG

Immune resilience & gut defense

Lactobacillus paracasei L9

Immune & respiratory support

Lactobacillus salivarius CD42

Oral & gut microbiome balance

Evidence-based Benefits

Composition-specific Benefits

Probionite™ is a 3-in-1 synbiotic formulation system developed with 10 probiotic strains, prebiotics, and digestive enzymes as part of a long-term daily gut wellness approach.

Reduction of Digestive Bloating

Selected probiotic strains help maintain a more balanced microbial environment in the gut¹ , reducing excessive gas buildup and digestive discomfort.

Increase Bowel Regularity

Prebiotics and targeted probiotic strains¹ help support healthy intestinal movement and microbial² activity, promoting more regular bowel movements and a smoother digestive rhythm.

Support Sleep & Stress Regulation

Targeted probiotic strains¹ help support the gut-brain axis and microbial balance, contributing to a calmer nervous system, improved stress resilience, and more stable sleep quality.

Enhanced Immune Defense

Clinically studied probiotic strains¹ help strengthen the gut microbiome barrier and support immune system activity, contributing to a more resilient and balanced internal defense system.

Improved Nutrient Absorption

Digestive enzymes¹ and targeted probiotic strains² help break down carbohydrates and proteins more efficiently, supporting better nutrient availability and absorption.

Reduced Inflammatory Response

Beneficial microbial strains¹ help support a healthier immune response and reducing inflammatory stress associated with intestinal imbalance (such as digestive sensitivity and gut discomfort).

Reduction of Digestive Bloating

Selected probiotic strains help maintain a more balanced microbial environment in the gut¹ , reducing excessive gas buildup and digestive discomfort.

Increase Bowel Regularity

Prebiotics and targeted probiotic strains¹ help support healthy intestinal movement and microbial² activity, promoting more regular bowel movements and a smoother digestive rhythm.

Support Sleep & Stress Regulation

Targeted probiotic strains¹ help support the gut-brain axis and microbial balance, contributing to a calmer nervous system, improved stress resilience, and more stable sleep quality.

Enhanced Immune Defense

Clinically studied probiotic strains¹ help strengthen the gut microbiome barrier and support immune system activity, contributing to a more resilient and balanced internal defense system.

Improved Nutrient Absorption

Digestive enzymes¹ and targeted probiotic strains² help break down carbohydrates and proteins more efficiently, supporting better nutrient availability and absorption.

Reduced Inflammatory Response

Beneficial microbial strains¹ help support a healthier immune response and reducing inflammatory stress associated with intestinal imbalance (such as digestive sensitivity and gut discomfort).

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Built to a Global Standard *

A synbiotic system goes beyond simply adding more strains. Probionite was carefully formulated around compatibility, balance, and long-term consistency for everyday use.

Freeze-Drying Technology

Our probiotic strains are preserved using freeze-drying technology to help maintain bacterial stability and viability throughout storage. This process protects sensitive strains from heat and moisture exposure while helping retain their activity over time.

Strain-Level Identification

Every probiotic strain in Probionite™ is selected and identified at the strain level, allowing each bacteria type to be precisely characterized beyond its general species classification.

Testing

Each formulation undergoes quality and stability testing to evaluate bacterial viability, purity, and consistency throughout production and shelf life, helping maintain formulation integrity over time.

53+ Clinical Studies *

* Over 53 international scientific studies help shape the standards behind Probionite™ — allowing every strain to be selected based on researched data rather than marketing claims alone.

Vitamin C

Immune function (RCT) - https://pubmed.ncbi.nlm.nih.gov/29099763/

Oxidative stress (RCT) - https://pubmed.ncbi.nlm.nih.gov/23440782/

Bromelain

Inflammation (Clinical) - https://pubmed.ncbi.nlm.nih.gov/23304525/

Digestive support (Clinical) - https://pubmed.ncbi.nlm.nih.gov/17217316/

Papain

Digestive enzyme (Study)
https://pubmed.ncbi.nlm.nih.gov/20635774/

Probiotic mixture

Brain-gut axis (Systematic review) - https://www.sciencedirect.com/science/article/pii/S2666459325000812

Stress reduction (RCT) - https://pubmed.ncbi.nlm.nih.gov/31418131/

Gut microbiota (RCT) - https://pubmed.ncbi.nlm.nih.gov/30626142/

Inflammation (RCT) - https://pubmed.ncbi.nlm.nih.gov/28962936/

Fucoidan

Immune modulation (Study) - https://pubmed.ncbi.nlm.nih.gov/23394808/

Anti-inflammatory (Study) - https://pubmed.ncbi.nlm.nih.gov/19735647/

Prebiotic

mixture

Cognition (RCT) - https://pubmed.ncbi.nlm.nih.gov/32116068/

Gut-brain axis (RCT) - https://pubmed.ncbi.nlm.nih.gov/30235659/

GOS + FOS

Gut microbiota (RCT) - https://pubmed.ncbi.nlm.nih.gov/20920376/

Bifidobacteria growth (RCT) - https://pubmed.ncbi.nlm.nih.gov/18709886/

Probiotic + Prebiotic

Synbiotic effect (RCT) - https://pubmed.ncbi.nlm.nih.gov/26081401/

Lactobacillus GG

Antibiotic-associated diarrhea (RCT) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539293/

Gut health & immunity (Meta-analysis) -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423603/

Respiratory infection (RCT) - https://pubmed.ncbi.nlm.nih.gov/19828107/

Children gut health (RCT) - https://pubmed.ncbi.nlm.nih.gov/12496262/

Diarrhea prevention (RCT) - https://pubmed.ncbi.nlm.nih.gov/15795546/

Immune response (RCT) - https://pubmed.ncbi.nlm.nih.gov/17429093/

Gut barrier function (RCT) - https://pubmed.ncbi.nlm.nih.gov/22267542/

Inflammation reduction (RCT) - https://pubmed.ncbi.nlm.nih.gov/23337950/

Microbiota balance (RCT) - https://pubmed.ncbi.nlm.nih.gov/24806753/

IBS symptoms (RCT) - https://pubmed.ncbi.nlm.nih.gov/18456523/

Bifidobacterium BB68S

Cognitive function (RCT) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824790/

IBS improvement (RCT) - https://pubmed.ncbi.nlm.nih.gov/31424528/

Gut microbiota (RCT) - https://pubmed.ncbi.nlm.nih.gov/22595701/

Stress & anxiety (RCT) - https://pubmed.ncbi.nlm.nih.gov/26706022/

Immune modulation (RCT) - https://pubmed.ncbi.nlm.nih.gov/20600857/

Galactooligosaccharides

Stress & cortisol (RCT) - https://pubmed.ncbi.nlm.nih.gov/27405838/

Anxiety reduction (RCT) - https://pubmed.ncbi.nlm.nih.gov/30511617/

Gut microbiota (RCT) - https://pubmed.ncbi.nlm.nih.gov/20920376/

Bifidobacteria growth (RCT) - https://pubmed.ncbi.nlm.nih.gov/18709886/

Digestive health (RCT) - https://pubmed.ncbi.nlm.nih.gov/17145738/

Fructooligosaccharides

Gut microbiota (RCT) - https://pubmed.ncbi.nlm.nih.gov/22282004/

Bifidobacteria increase (RCT) - https://pubmed.ncbi.nlm.nih.gov/11375796/

Digestion (RCT) - https://pubmed.ncbi.nlm.nih.gov/18469239/

Gut health (RCT) - https://pubmed.ncbi.nlm.nih.gov/10750102/

Immune markers (RCT) - https://pubmed.ncbi.nlm.nih.gov/12781846/

Inulin

Gut microbiota (Systematic review) - https://pubmed.ncbi.nlm.nih.gov/25244503/

Metabolic health (RCT) - https://pubmed.ncbi.nlm.nih.gov/23609775/

Bowel movement (RCT) - https://pubmed.ncbi.nlm.nih.gov/17384329/

Bifidobacteria increase (RCT) - https://pubmed.ncbi.nlm.nih.gov/11722958/

Weight & metabolism (RCT) - https://pubmed.ncbi.nlm.nih.gov/21109048/

Lactobacillus plantarum

Gut barrier (RCT) - https://pubmed.ncbi.nlm.nih.gov/26617117/

Inflammation (RCT) - https://pubmed.ncbi.nlm.nih.gov/23337950/

IBS (RCT) - https://pubmed.ncbi.nlm.nih.gov/24304668/

Lactobacillus rhamnosus

Anxiety (RCT) - https://pubmed.ncbi.nlm.nih.gov/25448230/

Gut-brain axis (RCT) - https://pubmed.ncbi.nlm.nih.gov/22986554/

Bifidobacterium animalis

Bowel movement (RCT) - https://pubmed.ncbi.nlm.nih.gov/21360761/

Digestion (RCT) - https://pubmed.ncbi.nlm.nih.gov/19815574/